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Latest App Notes & Case Studies

Sensitive Signature Peptide Quantification Using Accurate Mass Spectrometry
App Note / Case Study

Sensitive Signature Peptide Quantification Using Accurate Mass Spectrometry

This application note presents a highly sensitive signature peptide quantification workflow using cutting-edge accurate mass spectrometry technology.
Easy Set-Up for Protein Crystallization Experiments
App Note / Case Study

Easy Set-Up for Protein Crystallization Experiments

This app note highlights how a handheld electronic pipette can help researchers save time and increase homogeneous crystal growth.
Scientist with liquid sample
App Note / Case Study

Real-Time Quality Control Software for Metabolic Phenotyping

QC can be performed after data acquisition, but unexpected deviations can waste valuable time and resources. Instead, real-time QC allows for active monitoring of data quality as the analysis is being performed, preventing errors that can compromise the analysis.
Gene Helix
App Note / Case Study

Oligonucleotide Purity Analysis With Side-Product Identification and Quantitation

Oligonucleotides play a crucial role in modern drug development, therefore their accurate characterization is essential. However, given the sheer complexity and diversity of the types of oligonucleotides that are in clinical development, a range of diverse analytical approaches are necessary.
Protein Sequencing
App Note / Case Study

Protein Sequence Analysis: Next-Generation vs Mass Spectrometry Methods

Mass spectrometry is regarded as the gold standard for protein identification; however, this technique cannot easily discriminate between protein variants and is not accessible to everyday scientists due to the high cost, space and expertise required.
App Note / Case Study

Accelerate Discovery with SWATH DIA Mass Spectrometry

This application focus presents the exciting technology behind advances in DIA and discusses how it can be used to enhance research.
Bile acid
App Note / Case Study

Enhance Your Annotation Confidence in LC-TIMS-HRMS-Based Bile Acid Profiling

Bile acids are well known for their roles in cholesterol homeostasis, lipid absorption and as metabolic signaling molecules. They are implicated in a variety of disease states and therefore serve as an exciting focus on research in novel biomarker discovery.
Cell Culture Medium
App Note / Case Study

Cultivating Stem Cells: A Guide to Choosing the Right Culture Medium

Pluripotent stem cells are the gateway to creating cells for disease modeling, regeneration and drug discovery. When it comes to growing such infinite potential, selecting the right culture medium is key!
Plasma
App Note / Case Study

New Standards for Plasma Proteomics

Identifying novel biomarkers with bottom-up proteomics remains a substantial challenge due to the wide concentration ranges and potentially low abundance of important analytes.
MALDI Imaging
App Note / Case Study

Multiplex and Multiomic Imaging of Targeted Proteins and Small Molecules

Need a routine analytical technique that can provide protein expression profiling and targeted drug imaging? MALDI Imaging is used to determine the spatial distribution of molecules in a tissue section, for more complete multiomic information.
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