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An effective HIV vaccine may need to prompt strong responses from immune cells called CD8+ T cells to protect people from acquiring HIV, according to a new study from researchers at the National Institute of Allergy and Infectious Diseases (NIAID).

Membrane vesicles released by bacteria could be candidates for new vaccines against antibiotic-resistant enterococci bacteria that can be released naturally in the body.

One-letter difference in our DNA determines whether BCG vaccine provides good protection against tuberculosis or not. Researchers have elucidated how that one letter difference affects the activation and deactivation of the immune system.

Stem cell-based therapy improved quality of life for patients with advanced heart failure, Mayo Clinic researchers and international collaborators discovered in a late-stage multinational clinical trial.

Early results from a Phase I clinical trial of AT101, a new CAR T cell therapy that uses a distinct binding mechanism to target CD19, show a 100 percent complete response (CR) rate at the higher dose levels studied in the trial.

Tiny llama antibodies, called nanobodies, have been shown to effectively neutralize human noroviruses in the lab, revealing that they could be developed into a therapeutic agent.

The liver can produce an undesired immune response, triggered by gene therapy, the discovery of which may pave the way for a change in immunomodulation strategies for long-lasting gene therapies.

An under-the-skin implant that secretes insulin could provide an easier, long-term and less invasive way to treat type 1 diabetes.

Chimeric Antigen Receptors (CARs) have opened up an exciting new field of therapeutic advancements for rare and difficult-to-treat cancers, as they have the ability to deliver targeted therapies that can kill tumor cells.

According to research, inhibiting the galectin 1 protein, which is often over-expressed in hepatocellular carcinoma (HCC) using gene therapy can shrink HCC and increase the number of killer T cells inside tumors in mice.